Heart cancer is an extremely rare form of cancer that is divided into primary tumors of the heart and secondary tumors of the heart.
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Types
Primary
Most heart tumors begin with myxomas, fibromas, rhabdomyomas, and hamartomas, although malignant sarcomas (such as angiosarcoma or cardiac sarcoma) have been known to occur. In a study of 12,487 autopsies performed in Hong Kong seven cardiac tumors were found, most of which were benign. According to Mayo Clinic: "At Mayo Clinic, on average only one case of heart cancer is seen each year." In a study conducted in the Hospital of the Medical University of Vienna 113 primary cardiac tumour cases were identified in a time period of 15 years with 11 being malignant. The mean survival in the latter group of patients was found to be 26.2 ± 9.8 months.
Primary malignant cardiac tumors (PMCTs) are even more rare. The most recent published study about PMCTs used the Surveillance, Epidemiology and End-Results (SEER) Cancer Registry to study 497 patients with PMCTs who were diagnosed during 2000-201 in the United States. Most cases were angiosarcomas (27.3%) with an incidence of 0.107 per 1,000,000 person-years and Non- Hodgkin's lymphomas [NHL] (26.9%), with an incidence of 0.108 per 1,000,000 person-years. The incidence rate of NHL increased significantly over the study period, but the incidence of cardiac angiosarcomas did not. The overall survival of NHL wa found to be significantly better than angiosarcomas.
Another previous study using the Surveillance, Epidemiology and End-Results (SEER) Cancer Registry from 1973-2011 found 551 cases of PMCTs, with an incidence of 34 cases per million persons. The study also found that the incidence has doubled over the past four decades. The associated mortality was very high, with only 46% of patients alive after one year. Sarcomas and mesotheliomas had the worst survival, while lymphomas had better survival. When compared with extracardiac tumors, PMCTs had worse survival.
Secondary
Secondary or metastatic heart tumours are much more common than primary heart tumours, occurring even 100 times more often. Every tumour in theory can metastasise to the heart with the only exception being tumours of the central nervous system. Malignant melanomas frequently metastasize to the heart, and represent the tumour with the highest rate of cardiac metastases (in more than half of cases).
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Diagnosis
Patients with heart tumours usually have non-specific symptoms, such as dyspnea, thoracoabdominal pain, fatigue, hemoptysis, shortness of breath when lying down, nausea and vomiting, fever, weight loss, and night sweats. These symptoms mimic symptoms of other heart diseases, which can make diagnosis difficult. In most cases, the diagnosis is based on clinical history, echocardiography, a CT scan or an MRI scan. Cardiac tumours are often first diagnosed after the patient has had a stroke, an embolism caused by detached tumour tissue.
Treatment
Primary Tumours
Secondary Tumours
In most cases, patients with heart metastases have advanced tumour disease, with the heart being only one of the many places involved in the generalised tumour spread. At that stage of the disease, the patients will have already undergone extensive chemotherapy, radiation therapy or surgical procedures. Cardiac treatment is usually confined to palliative measures.
Notable cases
- Catherine of Aragon's candidate cause of death was heart cancer.
- Eric Carr, drummer of the rock band Kiss, died of heart cancer.
- John Brim, blues musician and original writer of "Ice Cream Man", later covered by Van Halen.
- Alexander Belov, Soviet basketball player.
Source of the article : Wikipedia
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